20 / 10 / 16
关于“在冠状动脉旁路移植术中比较静脉桥血管内镜和开放获取法的随机试验”一文医学翻译摘要学习情况，记录于此。
Randomized Trial of Endoscopic or Open Vein-Graft Harvesting for Coronary-Artery Bypass
摘要
Abstract
背景
BACKGROUND
隐静脉桥血管是冠状动脉旁路移植术（CABG）中最常用的桥血管。静脉桥血管获取技术对远期临床结局的影响尚未明确。
The saphenous-vein graft is the most common conduit for coronary-artery bypass grafting (CABG). The influence of the vein-graft harvesting technique on long-term clinical outcomes has not been well characterized.
笔记：
方法
METHODS
我们将对在美国退伍军人事务部（Veterans Affairs）16家心脏手术中心接受CABG的患者进行随机分组，分别应用静脉桥血管开放获取法或内镜获取法。主要结局是主要心脏不良事件（包括全因死亡、非致死性心肌梗死和再次血运重建）构成的复合结局。本研究还评估了腿部切口并发症。
We randomly assigned patients undergoing CABG at 16 Veterans Affairs cardiac surgery centers to either open or endoscopic vein-graft harvesting. The primary outcome was a composite of major adverse cardiac events, including death from any cause, nonfatal myocardial infarction, and repeat revascularization. Leg-wound complications were also evaluated.
笔记：
We randomly assigned patients undergoing CABG at 16 Veterans Affairs cardiac surgery centers to either open or endoscopic vein-graft harvesting.
知识点包括但不限于：assign to；either ... or ...；open or endoscopic vein-graft harvesting；undergo
结果
RESULTS
共有1,150例患者接受随机分组。在2.78年的中位随访期内，开放获取组和内镜获取组分别有89例患者（15.5%）和80例患者（13.9%）发生主要结局（风险比，1.12；95%置信区间 [CI]，0.83～1.51；P=0.47）。开放获取组和内镜获取组分别有46例患者（8.0%）和37例患者（6.4%）死亡（风险比，1.25；95% CI，0.81～1.92）；分别有34例患者（5.9%）和27例患者（4.7%）发生了心肌梗死（风险比，1.27；95% CI，0.77～2.11）；分别有35例患者（6.1%）和31例患者（5.4%）发生了血运重建（风险比，1.14；95% CI，0.70～1.85）。开放获取组和内镜获取组分别有18例患者（3.1%）和8例患者（1.4%）发生了腿部切口感染（相对危险度，2.26；95% CI，0.99～5.15）。
A total of 1150 patients underwent randomization. Over a median follow-up of 2.78 years, the primary outcome occurred in 89 patients (15.5%) in the open-harvest group and 80 patients (13.9%) in the endoscopic-harvest group (hazard ratio, 1.12; 95% confidence interval [CI], 0.83 to 1.51; P=0.47). A total of 46 patients (8.0%) in the open-harvest group and 37 patients (6.4%) in the endoscopic-harvest group died (hazard ratio, 1.25; 95% CI, 0.81 to 1.92); myocardial infarctions occurred in 34 patients (5.9%) in the open-harvest group and 27 patients (4.7%) in the endoscopic-harvest group (hazard ratio, 1.27; 95% CI, 0.77 to 2.11), and revascularization occurred in 35 patients (6.1%) in the open-harvest group and 31 patients (5.4%) in the endoscopic-harvest group (hazard ratio, 1.14; 95% CI, 0.70 to 1.85). Leg-wound infections occurred in 18 patients (3.1%) in the open-harvest group and in 8 patients (1.4%) in the endoscopic-harvest group (relative risk, 2.26; 95% CI, 0.99 to 5.15).
笔记：
结论
CONCLUSIONS
在接受CABG的患者中，我们发现在主要心脏不良事件的风险方面，静脉桥血管开放获取法和内镜获取法无显著差异（由美国退伍军人事务部研究与发展办公室合作研究项目[Cooperative Studies Program, Office of Research and Development, Department of Veterans Affairs]资助；REGROUP在ClinicalTrials.gov注册号为NCT01850082）。
Among patients undergoing CABG, we did not find a significant difference between open vein-graft harvesting and endoscopic vein-graft harvesting in the risk of major adverse cardiac events. (Funded by the Cooperative Studies Program, Office of Research and Development, Department of Veterans Affairs; REGROUP ClinicalTrials.gov number, NCT01850082 .)
笔记：